Serine/threonine-protein kinase TAO2, Thousand and one amino acid protein 2, Taok2, Kiaa0881
Product description
Taok2 may play a role in apoptotic morphological changes. May affect microtubule organization and stability. May play a role in the osmotic stress-MAPK8 pathway. Activates the JNK MAP kinase pathway through the specific activation of the upstream MKK3 and MKK6 kinases. Prevents MAP3K7-mediated activation of IKKA, and thus NF-kappa-B activation. Phosphorylates itself, MBP, activated MAPK8 and tubulins (By similarity).1) Blackshaw, S., et al. PLoS Biol.(9), E247 (2004) :
Immunogen
This Mouse Taok2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 415-443 amino acids from the Central region of mouse Taok2.
Western blot analysis in HL-60 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.