Serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. May exert this function by promoting GLI1 nuclear localization. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently (By similarity).1) Maloverjan, A., et al. J. Biol. Chem. 285(39):30079-30090(2010)
Immunogen
This Mouse Ulk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-262 amino acids from the Central region of mouse Ulk3.
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.