Phosphomannose isomerase catalyzes the interconversion of
fructose-6-phosphate and mannose-6-phosphate and plays a critical
role in maintaining the supply of D-mannose derivatives, which are
required for most glycosylation reactions. Mutations in the MPI
gene were found in patients with carbohydrate-deficient
glycoprotein syndrome, type Ib.1) Johnatty, S.E., et al. PLoS Genet.(7), E1001016 (2010) :
Immunogen
This MPI antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human MPI.
Western blot analysis in U251 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.