Application
Immunofluorescence of MTCH2 in Mouse Kidney cells with MTCH2 antibody at 20 μg/mL.Application
Immunohistochemistry of MTCH2 in mouse kidney tissue with MTCH2 antibody at 5 μg/mL.Application
Western blot analysis of MTCH2 in 293 cell lysate with MTCH2 antibody at 1 μg/mL.| Product Name | MTCH2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MTCH2 Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. MTCH2 is a member of the mitochondrial carrier protein family that catalyze the exchange of substrates across the inner mitochondrial membrane and is targeted by Bid, a pro-apoptotic Bcl-2 family member, in response to apoptotic signals, suggesting that MTCH2 may play a key role in the mitochondrial apoptosis pathway.1) Lockshin RA, Osborne B, and Zakeri Z. Cell death in the third millennium. Cell Death Differ.2000; 7:2-7. |
| Immunogen | MTCH2 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human MTCH2. The immunogen is located within amino acids 80 - 130 of MTCH2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| MTCH2 antibody can be used for detection of MTCH2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | Mtch2 |
|---|---|
| Alternative Names | MTCH2 Antibody: HSPC032 2310034D24Rik 4930539J07Rik Mitochondrial carrier homolog 2 |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (75%) |
Application
Immunofluorescence of MTCH2 in Mouse Kidney cells with MTCH2 antibody at 20 μg/mL.
Application
Immunohistochemistry of MTCH2 in mouse kidney tissue with MTCH2 antibody at 5 μg/mL.
Application
Western blot analysis of MTCH2 in 293 cell lysate with MTCH2 antibody at 1 μg/mL.| Positive Control | 1) Cat. No. 1210 - 293 Cell Lysate |
|---|---|
| Application Notes | MTCH2 antibody can be used for detection of MTCH2 by Western blot at 1 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | MTCH2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | MTCH2 Antibody is supplied in PBS containing 0.02% sodium azide. |
