Application
Immunohistochemistry of MTERFD2 in human small intestine tissue with MTERFD2 antibody at 2.5 μg/ml.Application
Immunofluorescence of MTERFD2 in human small intestine tissue with MTERFD2 antibody at 20 μg/ml.Application
Western blot analysis of MTERFD2 in human small intestine tissue lysate with MTERFD2 antibody at 1 μg/mL.| Product Name | MTERFD2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MTERFD2 Antibody: Members of the mTERF (mitochondrial transcription termination factor) family, are mitochondrial proteins that are believed to be transcription termination factors. MTERFD2 is targeted to the mitochondria and is ubiquitously expressed, with highest expression levels in fore- and midbrain, diencephalon, spinal cord, tongue, lung liver and kidney. MTERFD2 has been suggested to play a role in organ differentiation during embryogenesis. A closely related mTERF family member, MTERFD3, is believed to be involved in cell cycle regulation and cell growth by modulating mitochondrial transcription.1) Fernandez-Silva P, et al. The human mitochondrial transcription termination factor (mTERF) is a multizipper protein but binds to DNA as a monomer, with evidence pointing to intramolecular leucine zipper interactions. EMBO J. 1997; 16:1066-79. |
| Immunogen | MTERFD2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human MTERFD2 . The immunogen is located within amino acids 260 - 310 of MTERFD2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| MTERFD2 Antibody can be used for detection of MTERFD2 by Western blot at 1 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MTERFD2 |
|---|---|
| Alternative Names | MTERFD2 Antibody: MTERF4 mTERF domain-containing protein 2 Mitochondrial transcription termination factor 4 MTERF4 |
| Molecular Weight(MW) | Predicted: 42 kDa Observed: 44 kDa |
| Sequence Similarities | 2) Cat. No. 11-801 - Human Small Intestine Tissue Slide |
| Tissue Specificity | At least three isoforms of MTERFD2 are known to exist. MTERFD2 antibody is predicted to not cross-react with other MTERFD protein family members. |
Application
Immunohistochemistry of MTERFD2 in human small intestine tissue with MTERFD2 antibody at 2.5 μg/ml.
Application
Immunofluorescence of MTERFD2 in human small intestine tissue with MTERFD2 antibody at 20 μg/ml.
Application
Western blot analysis of MTERFD2 in human small intestine tissue lysate with MTERFD2 antibody at 1 μg/mL.| Positive Control | 1) Cat. No. 1308 - Human Small Intestine Tissue Lysate |
|---|---|
| Application Notes | MTERFD2 Antibody can be used for detection of MTERFD2 by Western blot at 1 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | MTERFD2 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. |
| Storage Buffer | MTERFD2 Antibody is supplied in PBS containing 0.02% sodium azide. |
