This gene encodes a myotubularin-related protein. The
encoded protein is a phosphoinositide phosphatase that specifically
dephosphorylates phosphatidylinositol 3,5-biphosphate and
phosphatidylinositol 3-phosphate. Mutations in this gene are
correlated with autosomal dominant centronuclear myopathy.
Alternate splicing results in multiple transcript variants. A
pseudogene of this gene is found on chromosome 18.1) Gibbs, E.M., et al. Autophagy 6(6):819-820(2010)
Immunogen
This MTMR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human MTMR14.
Western blot analysis in Hela cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.