The protein encoded by this gene was determined by in
silico methods to be a mitochondrial protein with similarity to the
peptide chain release factors (RFs) discovered in bacteria and
yeast. The peptide chain release factors direct the termination of
translation in response to the peptide chain termination codons.
Initially thought to have a role in the termination of mitochondria
protein synthesis, a recent publication found no mitochondrial
translation release functionality. Multiple alternatively spliced
transcript variants have been suggested by mRNA and EST data;
however, their full-length natures are not clear. [provided by
RefSeq].1) Antonicka, H., et al. Am. J. Hum. Genet. 87(1):115-122(2010)
Immunogen
This MTRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-259 amino acids from the Central region of human MTRF1.
Western blot analysis of lysate from human lung tissue lysate, using MTRF1 Antibody at 1:1000 at each lane.
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.