Application
Immunohistochemistry staining of Mucin 2 in colon: formalin-fixed, paraffin-embedded (ffpe)Mucin 2 Monoclonal Antibody.| Product Name | Mucin 2 Antibody [996/1] |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. IHC Control: Normal colon This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. |
| Immunogen | Mucin 2 monoclonal antibody was raised against a tandem repeat peptide of Mucin 2 (Human). |
| Clonality | Monoclonal |
|---|---|
| Isotype | IgG1 |
| Host Species | Mouse |
| Tested Applications | IHCWB |
| Mucin 2 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 10 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein G |
| Gene Symbol | MUC2 |
|---|---|
| Alternative Names | MUC2 Intestinal mucin-2 Mucin-like protein MUC-2 Mucin 2 intestinal/tracheal Mucin 2 Mucin-2 MLP SMUC |
| Tissue Specificity | Recognizes human Mucin 2 (MUC-2), and shows no cross-reactivity with MUC-1, MUC-3 or MUC-4. In tissue sectionsrecognizes colon, liver and prostate tissues strongly. The antibody recognizes malignant colonic mucosa as well as normal mucosa. |
Application
Immunohistochemistry staining of Mucin 2 in colon: formalin-fixed, paraffin-embedded (ffpe)Mucin 2 Monoclonal Antibody.| Application Notes | Mucin 2 antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 10 μg/mL. |
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| Form | Liquid |
|---|---|
| Storage Instructions | Store Mucin 2 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. Store undiluted. |
| Storage Buffer | PBS, pH 7.4, 0.09% sodium azide. |
