Application
MUTED Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.Application
Western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the detected MUTED protein (arrow).Application
Western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the detected MUTED protein (arrow).| Product Name | MUTED Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | This gene encodes a component of BLOC-1 (biogenesis of lysosome-related organelles complex 1). Components of this complex are involved in the biogenesis of organelles such as melanosomes and platelet-dense granules. A mouse model for Hermansky-Pudlak Syndrome is mutated in the murine version of this gene. Alternative splicing results in multiple transcript variants. Read-through transcription exists between this gene and the upstream EEF1E1 (eukaryotic translation elongation factor 1 epsilon 1) gene, as well as with the downstream TXNDC5 (thioredoxin domain containing 5) gene.1) Morris, D.W., et al. Biol. Psychiatry 63(1):24-31(2008) |
| Immunogen | This MUTED antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40-68 amino acids from the Central region of human MUTED. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 | |
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | BLOC1S5 |
|---|---|
| Alternative Names | Biogenesis of lysosome-related organelles complex 1 subunit 5 BLOC-1 subunit 5 Protein Muted homolog BLOC1S5 MUTED |
| Molecular Weight(MW) | 22 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Pig |
Application
MUTED Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Application
Western blot analysis in mouse bladder tissue lysates (15ug/lane).This demonstrates the detected MUTED protein (arrow).
Application
Western blot analysis in MDA-MB435 cell line lysates (15ug/lane).This demonstrates the detected MUTED protein (arrow).| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
