Application
Western blot analysis of MYCT1 in rat lung tissue lysate with MYCT1 antibody at (A) 1 and (B) 2 μg/mL.| Product Name | MYCT1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | MYCT1 Antibody: MYCT1 was initially identified as a novel target of the c-Myc oncogene in myeloid cells. It is a widely expressed nuclear protein whose overexpression can promote apoptosis, alteration of morphology, enhancement of anchorage-independent cell growth, tumorigenic conversion, promotion of genomic instability, and inhibition of hematopoietic differentiation. MYCT1 binds to the promoters of several c-Myc-regulated genes and it has been suggested that the phenotypes seen in MYCT1-overexpressing cells are a result of the deregulation of these genes. RUNX1-ETO, a fusion protein made up of RUNX1 and ETO, is thought to deregulate the proliferation and responsiveness of human hematopoietic progenitor cells downstream of MYCT1.1) Yin X, Grove L, Rogulski K, et al. Myc target in myeloid cells-1, a novel c-Myc target, recapitulates multiple c-Myc phenotypes. J. Biol. Chem. 2002; 277:19998-20010. |
| Immunogen | MYCT1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human MYCT1. The immunogen is located within the last 50 amino acids of MYCT1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μg/mL. | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | MYCT1 |
|---|---|
| Alternative Names | MYCT1 Antibody: MTLC MTLC MTMC1 Myc target protein 1 Myc target in myeloid cells protein 1 |
| Molecular Weight(MW) | 26 kDa |
| Tissue Specificity | At least two isoforms of MYCT1 are known to exist; this antibody will detect both isoforms. |
Application
Western blot analysis of MYCT1 in rat lung tissue lysate with MYCT1 antibody at (A) 1 and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1462 - Rat Lung Tissue Lysate |
|---|---|
| Application Notes | MYCT1 antibody can be used for detection of MYCT1 by Western blot at 1 - 2 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | MYCT1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | MYCT1 Antibody is supplied in PBS containing 0.02% sodium azide. |
