NALP14 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.1) Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.
Immunogen
NALP14 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP14. The immunogen is located within amino acids 200 - 250 of NALP14.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WB
NALP14 antibody can be used for detection of NALP14 by Western blot at 1 μg/mL.
Western blot analysis of NALP14 in rat brain tissue lysate with NALP14 antibody at 1 μg/mL.
Positive Control
1) Cat. No. 1463 - Rat Brain Tissue Lysate
Application Notes
NALP14 antibody can be used for detection of NALP14 by Western blot at 1 μg/mL.
Additional Information
Form
Liquid
Storage Instructions
NALP14 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Storage Buffer
NALP14 Antibody is supplied in PBS containing 0.02% sodium azide.