Application
Western blot analysis of NALP8 in human colon tissue lysate with NALP8 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Product Name | NALP8 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Product description | NALP8 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.1) Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104. |
| Immunogen | NALP8 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP8. The immunogen is located within amino acids 130 - 180 of NALP8. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| NALP8 antibody can be used for detection of NALP8 by Western blot at 1 μg/mL. | |
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NLRP8 |
|---|---|
| Alternative Names | NALP8 Antibody: PAN4 NALP8 NOD16 CLR19.2 PAN4 NACHT LRR and PYD domains-containing protein 8 Nucleotide-binding oligomerization domain protein 16 |
Application
Western blot analysis of NALP8 in human colon tissue lysate with NALP8 antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.| Positive Control | 1) Cat. No. 1320 - Human Colon Tissue Lysate |
|---|---|
| Application Notes | NALP8 antibody can be used for detection of NALP8 by Western blot at 1 μg/mL. |
| Form | Liquid |
|---|---|
| Storage Instructions | NALP8 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | NALP8 Antibody is supplied in PBS containing 0.02% sodium azide. |
