This gene is one of two arylamine N-acetyltransferase
(NAT) genes in the human geneome, and is orthologous to the mouse
and rat Nat2 genes. The enzyme encoded by this gene catalyzes the
transfer of an acetyl group from acetyl-CoA to various arylamine
and hydrazine substrates. This enzyme helps metabolize drugs and
other xenobiotics, and functions in folate catabolism. Multiple
transcript variants encoding different isoforms have been found for
this gene.1) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Immunogen
This NAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the Central region of human NAT1.
Western blot analysis in A375 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.