This gene encodes a member of the heparan sulfate/heparin
GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme
is a type II transmembrane protein that resides in the Golgi
apparatus. This monomeric bifunctional enzyme catalyzes the
N-deacetylation and N-sulfation of N-acetylglucosamine residues in
heparan sulfate and heparin, which are the initial chemical
modifications required for the biosynthesis of the functional
oligosaccharide sequences that define the specific ligand binding
activities of heparan sulfate and heparin.1) Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
Immunogen
This NDST3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 809-836 amino acids from the C-terminal region of human NDST3.
Western blot analysis in HL-60 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.