This gene encodes a subunit of the NADH:ubiquinone
oxidoreductase (complex I), which is the first enzyme complex in
the electron transport chain of mitochondria. This complex
functions in the transfer of electrons from NADH to the respiratory
chain. The subunit encoded by this gene is one of seven subunits in
the iron-sulfur protein fraction. Mutations in this gene cause
mitochondrial complex I deficiency, a disease that causes a wide
variety of clinical disorders, including neonatal disease and
adult-onset neurodegenerative disorders.1) Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)
Immunogen
This NDUFS6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the Central region of human NDUFS6.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.