Application
Western blot analysis of NEIL1 Antibody in A2058 cell line lysates (35ug/lane)| Product Name | NEIL1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Endonuclease 8-like 1, 322-, DNA glycosylase/AP lyase Neil1, DNA-(apurinic or apyrimidinic site) lyase Neil1, Endonuclease VIII-like 1, FPG1, Nei homolog 1, NEH1, Nei-like protein 1, NEIL1 |
| Product description | NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226]).1) Zhao, X., et al. Biochemistry 49(8):1658-1666(2010) |
| Immunogen | This NEIL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 130-159 amino acids from the Central region of human NEIL1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | NEIL1 |
|---|---|
| Alternative Names | Endonuclease 8-like 1 322- DNA glycosylase/AP lyase Neil1 DNA-(apurinic or apyrimidinic site) lyase Neil1 Endonuclease VIII-like 1 FPG1 Nei homolog 1 NEH1 Nei-like protein 1 NEIL1 |
| Molecular Weight(MW) | 44 kDa |
Application
Western blot analysis of NEIL1 Antibody in A2058 cell line lysates (35ug/lane)| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
