Application
Western blot analysis in HepG2 cell line lysates (35ug/lane).| Product Name | NEIL2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Endonuclease 8-like 2, 322-, DNA glycosylase/AP lyase Neil2, DNA-(apurinic or apyrimidinic site) lyase Neil2, Endonuclease VIII-like 2, Nei homolog 2, NEH2, Nei-like protein 2, NEIL2 |
| Product description | NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])1) Briggs, F.B., et al. Am. J. Epidemiol. 172(2):217-224(2010) |
| Immunogen | This NEIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human NEIL2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NEIL2 |
|---|---|
| Alternative Names | Endonuclease 8-like 2 322- DNA glycosylase/AP lyase Neil2 DNA-(apurinic or apyrimidinic site) lyase Neil2 Endonuclease VIII-like 2 Nei homolog 2 NEH2 Nei-like protein 2 NEIL2 |
| Molecular Weight(MW) | 37 kDa |
Application
Western blot analysis in HepG2 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
