Neogenin, Immunoglobulin superfamily DCC subclass member 2, NEO1, IGDCC2, NGN
Product description
This gene encodes a cell surface protein that is a member
of the immunoglobulin superfamily. The encoded protein consists of
four N-terminal immunoglobulin-like domains, six fibronectin type
III domains, a transmembrane domain and a C-terminal internal
domain that shares homology with the tumor suppressor candidate
gene DCC. This protein may be involved in cell growth and
differentiation and in cell-cell adhesion. Defects in this gene are
associated with cell proliferation in certain cancers. Alternate
splicing results in multiple transcript variants. [provided by
RefSeq].1) Bradford, D., et al. J. Comp. Neurol. 518(16):3237-3253(2010)
Immunogen
This NEO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 657-685 amino acids from the Central region of human NEO1.
Western blot analysis in mouse spleen tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.