Application
Immunohistochemistry staining of NF2 in brain cortex tissue using NF2 Antibody.| Product Name | Neurofibromin 2 (phospho Ser518) Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NF2, ACN, BANF, Moesin-ezrin-radixin like, Neurofibromin 2 (merlin), Neurofibromin-2, SCH, Merlin, Schwannomerlin, Schwannomin |
| Product description | The recently isolated neurofibromatosis 2 tumor suppressor gene encodes a 595 amino acid protein (Merlin). The protein product Merlin, named for its relatedness to the ezrin, radixin and moesin (ERM) family of proteins, is a tumor suppressor whose absence results in the occurrence of multiple tumors of the nervous system, particularly schwannomas and meningiomas. Merlin's similarity to ERMs suggests that it might share functions, acting as a link between cytoskeletal components and the cell membrane. The NF2 protein is highly expressed in human fibroblasts and is detected as a single band of about 75 kDa. This antibody is specific for the phosphorylated form of human NF2 (Merlin). |
| Immunogen | Human NF2 (Merlin) phospho-peptide corresponding to a region of the human protein surrounding S518 and conjugated to Keyhole Limpet Hemocyanin (KLH). |
| Modification | p-Ser518 |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAIHCIPWB |
| Neurofibromin 2 antibody can be used in ELISA, and immunohistochemistry starting at 2.5 μg/mL.: |
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| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NF2 |
|---|---|
| Alternative Names | NF2 ACN BANF Moesin-ezrin-radixin like Neurofibromin 2 (merlin) Neurofibromin-2 SCH Merlin Schwannomerlin Schwannomin |
| Tissue Specificity | pSer518 |
Application
Immunohistochemistry staining of NF2 in brain cortex tissue using NF2 Antibody.| Application Notes | Neurofibromin 2 antibody can be used in ELISA, and immunohistochemistry starting at 2.5 μg/mL.: |
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| Form | Liquid |
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| Storage Instructions | Store Neurofibromin 2 antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide. |
