Application
Antibody is used in Western blot to detect NeuroG1 in A375 cell lysate.Application
Western Blot at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.| Product Name | Neurogenin1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Neurogenin-1, NGN-1, Class A basic helix-loop-helix protein 6, bHLHa6, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, NeuroD3, NEUROG1, BHLHA6, NEUROD3, NGN, NGN1 |
| Product description | Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis.1) Tamimi, R.M., et al., Genomics 40(2):355-357 (1997). |
| Immunogen | This Neurogenin1 (NeuroG1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human Neurogenin1 (NeuroG1). |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NEUROG1 |
|---|---|
| Alternative Names | Neurogenin-1 NGN-1 Class A basic helix-loop-helix protein 6 bHLHa6 Neurogenic basic-helix-loop-helix protein Neurogenic differentiation factor 3 NeuroD3 NEUROG1 BHLHA6 NEUROD3 NGN NGN1 |
| Molecular Weight(MW) | 26 kDa |
Application
Antibody is used in Western blot to detect NeuroG1 in A375 cell lysate.
Application
Western Blot at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
