Application
Immunohistochemistry staining of Nibrin in testis tissue using Nibrin Antibody.| Product Name | Nibrin Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NBN, ATV, AT-V2, Nibrin, NBS1, AT-V1, NBS, p95 |
| Product description | Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Immunogen | Nibrin antibody was raised against recombinant (partial) C-Terminal region of Nibrin (Mouse). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFIHCWB |
| Nibrin antibody can be used in Western Blot starting at 1:1000 - 1:5000, immunohistochemistry starting at 20 μg/mL, immunocytochemistry starting at 1:100 - 1:500, immunoprecipitation, and flow cytometry.: |
|
| Species Reactivity | HumanMouse |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NBN |
|---|---|
| Alternative Names | NBN ATV AT-V2 Nibrin NBS1 AT-V1 NBS p95 |
Application
Immunohistochemistry staining of Nibrin in testis tissue using Nibrin Antibody.| Application Notes | Nibrin antibody can be used in Western Blot starting at 1:1000 - 1:5000, immunohistochemistry starting at 20 μg/mL, immunocytochemistry starting at 1:100 - 1:500, immunoprecipitation, and flow cytometry.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store Nibrin antibody at 4 ˚C or -20 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 50% glycerol. |
Data sheet for OM286193