This gene encodes a protein that is involved in the
activation of the ubiquitous transcription factor NF-kappaB. This
protein is associated with the the histone deacetylase HDAC3 and
with the Notch corepressor complex, and it thereby acts as a
transcriptional repressor of Notch target genes. It is also
required for alphabeta T cell development. A related pseudogene has
been identified on chromosome X, while a related and intronless
retrocopy, which has an intact CDS and may be functional, is
located on chromosome 6.1) D'Addabbo, A., et al. Artif Intell Med 46(2):131-138(2009)
Immunogen
This NKAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human NKAP.
Western blot analysis in HepG2 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.