Protein naked cuticle homolog 1, Naked-1, hNkd, hNkd1, NKD1, NKD
Product description
In the mouse, Nkd is a Dishevelled (see DVL1; MIM 601365)-binding protein that functions as a negative regulator of the Wnt (see WNT1; MIM 164820)-beta-catenin (see MIM 116806)-Tcf (see MIM 602272) signaling pathway.1) Guo, J., et al. PLoS ONE(11), E7982 (2009)Creyghton, M.P., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5397-5402(2006) Creyghton, M.P., et al. Genes Dev. 19(3):376-386(2005) Yan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 98(26):14973-14978(2001) Katoh, M. Int. J. Oncol. 19(5):963-969(2001)
Immunogen
This NKD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-111 amino acids from the N-terminal region of human NKD1.
Western blot analysis in mouse lung,heart,bladder tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.