The coenzyme NAD and its derivatives are involved in
hundreds of metabolic redox reactions and are utilized in protein
ADP-ribosylation, histone deacetylation, and in some Ca(2+)
signaling pathways. NMNAT (EC 2.7.7.1) is a central enzyme in NAD
biosynthesis, catalyzing the condensation of nicotinamide
mononucleotide (NMN) or nicotinic acid mononucleotide (NaMN) with
the AMP moiety of ATP to form NAD or NaAD (Zhang et al., 2003
[PubMed 12574164]).1) Di Stefano, M., et al. Blood Cells Mol. Dis. 45(1):33-39(2010)
Immunogen
This NMNAT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 150-178 amino acids from the Central region of human NMNAT3.
Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.