NADPH oxidases (NOXs) catalyze the transfer of electrons from NADPH to molecular oxygen to generate reactive oxygen species (ROS). The NOX activator NOXA1 can stimulate both NOX1 (MIM 300225) and NOX2 (CYBB; MIM 300481), but it appears to be more effective in activating NOX1 (Opitz et al., 2007 [PubMed 17189823]).[supplied by OMIM].1) Niu, X.L., et al. Circulation 121(4):549-559(2010)
Immunogen
This NOXA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 449-478 amino acids from the C-terminal region of human NOXA1.
Western blot analysis of NOXA1 Antibody in MDA-MB435 cell line lysates (35ug/lane)
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.