NADPH oxidase organizer 1, NADPH oxidase regulatory protein, Nox organizer 1, Nox-organizing protein 1, SH3 and PX domain-containing protein 5, NOXO1, P41NOX, SH3PXD5
Product description
NADPH oxidases (NOXs) catalyze the transfer of electrons
from NADPH to molecular oxygen to generate reactive oxygen species
(ROS). NOX organizers, such as NOXO1, target NOX activators (see
NOXA1; MIM 611255) to NOX and also target NOX to different
subcellular compartments (Opitz et al., 2007 [PubMed
17189823]).1) Dutta, S., et al. PLoS ONE(5), E10478 (2010) :
Immunogen
This NOXO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-219 amino acids from the Central region of human NOXO1.
Western blot analysis in HL-60 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.