Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Product Name | NPLOC4 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Nuclear protein localization protein 4 homolog, Protein NPL4, NPLOC4, KIAA1499, NPL4 |
| Product description | The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity).1) Liu, F., et al. PLoS Genet. 6, E1000934 (2010) : |
| Immunogen | This NPLOC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-484 amino acids from the C-terminal region of human NPLOC4. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | NPLOC4 |
|---|---|
| Alternative Names | Nuclear protein localization protein 4 homolog Protein NPL4 NPLOC4 KIAA1499 NPL4 |
| Molecular Weight(MW) | 68 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Mouse |
Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
