Application
Antibody used in WB on Human Jurkat 2.5 ug/ml.| Product Name | NR1H3 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NR1H3, LXRA, LXR-a, RLD-1 |
| Product description | Interaction of NR1H3 with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. NR1H3 are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. NR1H3 Plays an important role in the regulation of cholesterol homeostasis.1) Albers, M., et al., (2006) J. Biol. Chem. 281 (8), 4920-4930. |
| Immunogen | Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR1H3. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | ELISAWB |
| NR1H3 antibody can be used for detection of NR1H3 by ELISA at 1:1562500. NR1H3 antibody can be used for detection of NR1H3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Protein A |
| Gene Symbol | NR1H3 |
|---|---|
| Alternative Names | NR1H3 LXRA LXR-a RLD-1 |
| Molecular Weight(MW) | 50 kDa |
Application
Antibody used in WB on Human Jurkat 2.5 ug/ml.| Positive Control | 1) Cat. No. 1205 - Jurkat Cell Lysate |
|---|---|
| Application Notes | NR1H3 antibody can be used for detection of NR1H3 by ELISA at 1:1562500. NR1H3 antibody can be used for detection of NR1H3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.: |
| Form | Liquid |
|---|---|
| Storage Instructions | For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR1H3 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles. |
| Storage Buffer | IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt |
