Nurim is an inner nuclear membrane (INM) protein that is tightly associated with the inner nuclear membrane. It was first isolated in a visual screen for nuclear envelope-localizing proteins. In subcellular fractionation, nurim remained extremely tightly bound to nuclear fractions. Unlike the known nuclear envelope (NE) membrane proteins, it is neither associated with nuclear pores, nor targeted like lamin-associated membrane proteins suggesting its localization to NE by a distinct mechanism.
Immunogen
A portion of amino acids 200-250 of human Nurim.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
IHCWB
NRM antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, and immunohistochemistry starting at 5 μg/mL.: