Calnuc or NUCB1 belongs to the nucleobindin family. It is a major calcium-binding protein of the Golgi and is a good Golgi marker. It may be involved in calcium homeostasis. Calnuc also plays roles in regulation of levels of .-amyloid precursor protein (APP) and its proteolytic metabolites to further affect the patho/physiological functions of APP including Alzheimer's disease pathogenesis. Useful for immunohistochemistry and western blot.1) Huaxi Xu, et al., (2007) Journal of Neurochemistry 100:1505.
Immunogen
Antibody produced in rabbits immunized with a synthetic KLH-conjugated peptide corresponding a region of human NUCB1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISA
NUCB1 antibody can be used for detection of NUCB1 by ELISA at 1:1562500.:
NUCB1 antibody can be used for detection of NUCB1 by ELISA at 1:1562500.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NUCB1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.Store at -20 °C.Stable for 12 months from date of receipt