Western blot analysis of NUDT2 using rabbit polyclonal NUDT2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the NUDT2 gene.
This gene encodes a member of the MutT family of
nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase
family. The gene product possesses a modification of the MutT
sequence motif found in certain nucleotide pyrophosphatases. The
enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is
responsible for maintaining the intracellular level of the
dinucleotide Ap4A, the function of which has yet to be established.
This gene may be a candidate tumor suppressor gene. Alternative
splicing has been observed at this locus and three transcript
variants, all encoding the same protein, have been identified.1) Vasilenko, N., et al. Virol. J. 7, 31 (2010) :
Immunogen
This NUDT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the Central region of human NUDT2.
Western blot analysis of NUDT2 using rabbit polyclonal NUDT2 Antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the NUDT2 gene.
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.