The nuclear pore complex is a massive structure that
extends across the nuclear envelope, forming a gateway that
regulates the flow of macromolecules between the nucleus and the
cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the
main components of the nuclear pore complex in eukaryotic cells.
The protein encoded by this gene belongs to the nucleoporin family
and is associated with the oncogenic nucleoporin CAN/Nup214 in a
dynamic subcomplex. This protein is also overexpressed in a large
number of malignant neoplasms and precancerous dysplasias.1) Hashizume, C., et al. Mol. Cancer 9, 119 (2010) :
Immunogen
This NUP88 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 701-730 amino acids from the C-terminal region of human NUP88.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.