This gene is one member of a family of nuclear RNA export
factor genes. The encoded protein can bind RNA, and is implicated
in mRNA nuclear export. However, this protein has lost several
C-terminal protein domains found in other family members that are
required for export activity, and may be an evolving pseudogene.
Alternatively spliced transcript variants have been described, but
most are candidates for nonsense-mediated decay (NMD) and may not
express proteins in vivo.1) Tarpey, P.S., et al. Nat. Genet. 41(5):535-543(2009)
Immunogen
This NXF5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-80 amino acids from the N-terminal region of human NXF5.
Western blot analysis in Jurkat cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.