CST complex subunit STN1, Oligonucleotide/oligosaccharide-binding fold-containing protein 1, Suppressor of cdc thirteen homolog, OBFC1, STN1
Product description
OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha
accessory factor (AAF) that stimulates the activity of DNA
polymerase-alpha-primase (see MIM 176636), the enzyme that
initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]).
OBFC1 also appears to function in a telomere-associated complex
with C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009
[PubMed 19854130]).1) Levy, D., et al. Proc. Natl. Acad. Sci. U.S.A. 107(20):9293-9298(2010)
Immunogen
This OBFC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-306 amino acids from the C-terminal region of human OBFC1.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.