Application
Western blot analysis of lysed extracts from JK, HepG2 and 293 cells using Oct-1 Antibody.| Product Name | Oct-1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | OCT1, OTF1, oct-1B, 41183 |
| Product description | Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by NR3C1, AR and PGR By similarity. In case of human herpes simplex virus (HSV) infection, POU2F1 forms a multiprotein-DNA complex with the viral transactivator protein VP16 and HCFC1 thereby enabling the transcription of the viral immediate early genes.1) Prefontaine G. G., Walther R., Giffin W., Lemieux M. E., Pope L., Hache R. J. G. J. Biol. Chem, 274:26713-26719 (1999) Mahajan S. S., Wilson A. C. Mol. Cell. Biol. 20:919-928 (2000) |
| Immunogen | Oct-1 antibody was raised against a peptide sequence around aa.270~274 (T-P-K-R-I) derived from Human Oct-1. |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | WB |
| Western Blot: 1:500~1:1000: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | POU2F1 |
|---|---|
| Alternative Names | OCT1 OTF1 oct-1B 41183 |
| Molecular Weight(MW) | 90 kDa |
| Tissue Specificity | This antibody detects endogenous level of total Oct-1protein. |
| Entrez Gene | 5451 |
|---|---|
| Protein Accession | NP_001185712.1 |
Application
Western blot analysis of lysed extracts from JK, HepG2 and 293 cells using Oct-1 Antibody.| Application Notes | Western Blot: 1:500~1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store antibody at -20˚C for up to one year. |
| Storage Buffer | Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
