This gene encodes the rate-limiting enzyme of the
polyamine biosynthesis pathway which catalyzes ornithine to
putrescine. The activity level for the enzyme varies in response to
growth-promoting stimuli and exhibits a high turnover rate in
comparison to other mammalian proteins. Originally localized to
both chromosomes 2 and 7, the gene encoding this enzyme has been
determined to be located on 2p25, with a pseudogene located on
7q31-qter.1) Chaturvedi, R., et al. Gastroenterology 139(5):1686-1698(2010)
Immunogen
This ODC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-352 amino acids from the C-terminal region of human ODC1.
Western blot analysis in K562 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.