Olfactory receptors interact with odorant molecules in the
nose, to initiate a neuronal response that triggers the perception
of a smell. The olfactory receptor proteins are members of a large
family of G-protein-coupled receptors (GPCR) arising from single
coding-exon genes. Olfactory receptors share a 7-transmembrane
domain structure with many neurotransmitter and hormone receptors
and are responsible for the recognition and G protein-mediated
transduction of odorant signals. The olfactory receptor gene family
is the largest in the genome. The nomenclature assigned to the
olfactory receptor genes and proteins for this organism is
independent of other organisms. This olfactory receptor gene has a
coding sequence that is comparable in length to other olfactory
receptor genes, but it should be noted that a frameshift is present
in the 3' coding region that disrupts the 7-transmembrane domain
structure in the protein. It is unclear if the protein can function
as an olfactory receptor or if an alternate function is served. For
this reason, this gene has also been interpreted to be a
pseudogene.1) Fuchs, T., et al. Genomics 80(3):295-302(2002)
Immunogen
This OR2W5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human OR2W5.
Western blot analysis in WiDr cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.