The origin recognition complex (ORC) is a highly conserved
six subunit protein complex essential for the initiation of the DNA
replication in eukaryotic cells. Studies in yeast demonstrated that
ORC binds specifically to origins of replication and serves as a
platform for the assembly of additional initiation factors such as
Cdc6 and Mcm proteins. The protein encoded by this gene is a
subunit of the ORC complex. Alternatively spliced transcript
variants encoding distinct isoforms have been described. [provided
by RefSeq].1) Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Immunogen
This ORC5L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the Central region of human ORC5L.
Western blot analysis in mouse brain tissue lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.