Application
Immunofluorescence of ORMDL1 in mouse brain tissue with ORMDL1 antibody at 20 μg/mL.Application
Immunohistochemistry of ORMDL1 in mouse brain tissue with ORMDL1 antibody at 5 μg/mL.Application
Western blot analysis of ORMDL1 in SK-N-SH Cell lysate with ORMDL1 antibody at (A) 1 μg/mL and (B) 2 μg/mL.| Product Name | ORMDL1 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ORMDL1 Antibody: ORM1-like protein 1, Adoplin-1 |
| Product description | ORMDL1 Antibody: The ORMDL (ORM1-like) family of proteins consist of ORMDL1, ORMDL2 and ORMDL3 that may play roles in gamma-secretase complex maturation. Localized to the membrane of the endoplasmic reticulum, ORMDLs are widely expressed and are implicated in the expression of Presenilin (PSI) which is involved in Alzheimer's disease (AD). Expression of ORMDL1 is down-regulated in PSI mutations, suggesting a possible role as a therapeutic target for AD. ORMDLs have recently been identified as a potential risk factor for childhood asthma.1) Hjelmqvist L, Tuson M, Marfany G, et al. ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins. Genome Biol. 2002; 3(6): RESEARCH0027 |
| Immunogen | ORMDL1 antibody was raised against a 16 amino acid synthetic peptide of human ORMDL1. The immunogen is located within amino acids 50 - 100 of ORMDL1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIHC-PWB |
| ORMDL1 antibody can be used for detection of ORMDL1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | ORMDL1 |
|---|---|
| Alternative Names | ORMDL1 Antibody: ORM1-like protein 1 Adoplin-1 |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Bovine: (100%) |
| Tissue Specificity | ORMDL1 antibody may cross-react with other ORMDL protein family members. |
Application
Immunofluorescence of ORMDL1 in mouse brain tissue with ORMDL1 antibody at 20 μg/mL.
Application
Immunohistochemistry of ORMDL1 in mouse brain tissue with ORMDL1 antibody at 5 μg/mL.
Application
Western blot analysis of ORMDL1 in SK-N-SH Cell lysate with ORMDL1 antibody at (A) 1 μg/mL and (B) 2 μg/mL.| Positive Control | 1) Cat. No. 1220 - SK-N-SH Cell Lysate |
|---|---|
| Application Notes | ORMDL1 antibody can be used for detection of ORMDL1 by Western blot at 1 - 2 μg/mL. Antibody can also be used for immunohistochemistry starting at 5 μg/mL. For immunofluorescence start at 20 μg/mL.: |
| Form | Liquid |
|---|---|
| Storage Instructions | ORMDL1 antibody can be stored at 4 ˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | ORMDL1 Antibody is supplied in PBS containing 0.02% sodium azide. |
