P2X purinoceptor 3, P2X3, ATP receptor, Purinergic receptor, P2RX3
Product description
The product of this gene belongs to the family of
purinoceptors for ATP. This receptor functions as a ligand-gated
ion channel and may transduce ATP-evoked nociceptor activation.
Mouse studies suggest that this receptor is important for
peripheral pain responses, and also participates in pathways
controlling urinary bladder volume reflexes. It is possible that
the development of selective antagonists for this receptor may have
a therapeutic potential in pain relief and in the treatment of
disorders of urine storage.1) Allsopp, R.C., et al. J. Biol. Chem. 285(43):32770-32777(2010)
Immunogen
This P2RX3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 330-356 amino acids from the C-terminal region of human P2RX3.
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.