The protein encoded by this gene belongs to the family of
P2X receptors, which are ATP-gated ion channels and mediate rapid
and selective permeability to cations. This gene is predominantly
expressed in skeletal muscle, and regulated by p53. The encoded
protein is associated with VE-cadherin at the adherens junctions of
human umbilical vein endothelial cells. Alternative splicing
results in multiple transcript variants. A related pseudogene,
which is also located on chromosome 22, has been identified.1) Trynka, G., et al. Gut 58(8):1078-1083(2009)
Immunogen
This P2RX6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human P2RX6.
Western blot analysis in 293 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.