The protein encoded by this gene belongs to the innexin
family. Innexin family members are the structural components of gap
junctions. This protein and pannexin 1 are abundantly expressed in
central nervous system (CNS) and are coexpressed in various
neuronal populations. Studies in Xenopus oocytes suggest that this
protein alone and in combination with pannexin 1 may form cell
type-specific gap junctions with distinct properties. Multiple
transcript variants encoding different isoforms have been found for
this gene.1) Ambrosi, C., et al. J. Biol. Chem. 285(32):24420-24431(2010)
Immunogen
This PANX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 647-677 amino acids from the C-terminal region of human PANX2.
Western blot analysis in A549 cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.