Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PPBP antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.Application
Western Blot at 1:1000 dilution + human spleen lysate Lysates/proteins at 20 ug per lane.| Product Name | PBP Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Platelet basic protein, PBP, C-X-C motif chemokine 7, Leukocyte-derived growth factor, LDGF, Macrophage-derived growth factor, MDGF, Small-inducible cytokine B7, Connective tissue-activating peptide III, CTAP-III, LA-PF4, Low-affinity platelet factor IV, T |
| Product description | PPBP is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and sythesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells.1) Majumdar S.,J. Biol. Chem. 266:5785-5789(1991) |
| Immunogen | This PBP (PPBP) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 97-128 amino acids from the C-terminal region of human PBP (PPBP). |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC-PWB |
| For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Symbol | PPBP |
|---|---|
| Alternative Names | Platelet basic protein PBP C-X-C motif chemokine 7 Leukocyte-derived growth factor LDGF Macrophage-derived growth factor MDGF Small-inducible cytokine B7 Connective tissue-activating peptide III CTAP-III LA-PF4 Low-affinity platelet factor IV T |
| Molecular Weight(MW) | 14 kDa |
Application
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PPBP antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Application
Western Blot at 1:1000 dilution + human spleen lysate Lysates/proteins at 20 ug per lane.| Application Notes | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
