PBX1 binds the sequence 5'-ATCAATCAA-3'. It acts as a transcriptional activator of PF4 in complex with MEIS1. It may be converted into a potent transcriptional activator by the (1;19) translocation. It also may have a role in steroidogenesis and, subsequently, sexual development and differentiation.1) Wang, H., (2005) Mol. Genet. Metab. 86 (3), 384-391.
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PBX1.
Key Feature
Clonality
Polyclonal
Host Species
Rabbit
Tested Applications
ELISAWB
PBX1 antibody can be used for detection of PBX1 by ELISA at 1:312500. PBX1 antibody can be used for detection of PBX1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
PBX1 antibody can be used for detection of PBX1 by ELISA at 1:312500. PBX1 antibody can be used for detection of PBX1 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.:
Additional Information
Form
Liquid
Storage Instructions
For short periods of storage (days) store at 4˚C. For longer periods of storage, store PBX1 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Storage Buffer
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.