Application
Western blot analysis in A549 cell line lysates (35ug/lane).| Product Name | PCGF2 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Polycomb group RING finger protein 2, DNA-binding protein Mel-18, RING finger protein 110, Zinc finger protein 144, PCGF2, MEL18, RNF110, ZNF144 |
| Product description | The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.1) Jung, J.H., et al. Biochem. Biophys. Res. Commun. 400(4):523-530(2010) |
| Immunogen | This PCGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-150 amino acids from the Central region of human PCGF2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PCGF2 |
|---|---|
| Alternative Names | Polycomb group RING finger protein 2 DNA-binding protein Mel-18 RING finger protein 110 Zinc finger protein 144 PCGF2 MEL18 RNF110 ZNF144 |
| Molecular Weight(MW) | 38 kDa |
Application
Western blot analysis in A549 cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
