Phosducin, PHD, 33 kDa phototransducing protein, Protein MEKA, PDC
Product description
This gene encodes a phosphoprotein, which is located in
the outer and inner segments of the rod cells in the retina. This
protein may participate in the regulation of visual
phototransduction or in the integration of photoreceptor
metabolism. It modulates the phototransduction cascade by
interacting with the beta and gamma subunits of the retinal
G-protein transducin. This gene is a potential candidate gene for
retinitis pigmentosa and Usher syndrome type II. Alternatively
spliced transcript variants encoding different isoforms have been
identified.1) Beetz, N., et al. J. Clin. Invest. 119(12):3597-3612(2009)
Immunogen
This PDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the Central region of human PDC.
Western blot analysis in CEM cell line lysates (35ug/lane).
Application Notes
For WB starting dilution is: 1:1000:
Additional Information
Form
Liquid
Storage Instructions
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.