Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Product Name | PDCD10 Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Programmed cell death protein 10, Cerebral cavernous malformations 3 protein, TF-1 cell apoptosis-related protein 15, PDCD10, CCM3, TFAR15 |
| Product description | This gene encodes an evolutionarily conserved protein associated with cell apoptosis. The protein interacts with the serine/threonine protein kinase MST4 to modulate the extracellular signal-regulated kinase (ERK) pathway. It also interacts with and is phosphoryated by serine/threonine kinase 25, and is thought to function in a signaling pathway essential for vascular developent. Mutations in this gene are one cause of cerebral cavernous malformations, which are vascular malformations that cause seizures and cerebral hemorrhages. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].1) Lauenborg, B., et al. APMIS 118(10):719-728(2010) |
| Immunogen | This PDCD10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-124 amino acids from the Central region of human PDCD10. |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| For WB starting dilution is: 1:1000: |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PDCD10 |
|---|---|
| Alternative Names | Programmed cell death protein 10 Cerebral cavernous malformations 3 protein TF-1 cell apoptosis-related protein 15 PDCD10 CCM3 TFAR15 |
| Molecular Weight(MW) | 25 kDa |
| Sequence Similarities | Predicted species reactivity based on immunogen sequence: Zebrafish |
Application
Western blot analysis in CEM cell line lysates (35ug/lane).| Application Notes | For WB starting dilution is: 1:1000: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures. |
| Storage Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
