Application
Immunohistochemistry staining of PDE2A in kidney tissue using PDE2A Antibody.| Product Name | PDE2A Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDE2A, CGMP-stimulated PDE, Cyclic GMP-stimulated PDE, PDE2, Pde2a2, PED2A4, Phosphodiesterase 2A, CGS-PDE, CGSPDE, PDE2A1, Pde2a3 |
| Product description | Phosphodiesterase 2A is a cGMP stimulated, cAMP/cGMP dual-specific phosphodiesterase whose hydrolytic activity is stimulated by the presence of cGMP binding to the GAF domain. PDE2A has been implicated in penile erectile dysfunction and in the regulation of fluid and inflammatory cell transit across the endothelial cell barrier (i.e., venous and capillary). PDE2A activity is inhibited by erythro-9-(2-hydroxyl-3-nonyl)adenine (EHNA). At least three isoforms have been reported (PDE2A1, PDE2A2, and PDE2A3). |
| Immunogen | PDE2A antibody was raised against a peptide located in the N-Terminal region of PDE2A (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| PDE2A antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|
| Species Reactivity | DogGorillaHorseHuman |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PDE2A |
|---|---|
| Alternative Names | PDE2A CGMP-stimulated PDE Cyclic GMP-stimulated PDE PDE2 Pde2a2 PED2A4 Phosphodiesterase 2A CGS-PDE CGSPDE PDE2A1 Pde2a3 |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins, except KCNH2 (59%). |
Application
Immunohistochemistry staining of PDE2A in kidney tissue using PDE2A Antibody.| Application Notes | PDE2A antibody can be used in ELISA, Western Blot, and immunohistochemistry starting at 5 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | PDE2A antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
