Application
Immunohistochemistry staining of PDE8B in thyroid tissue using PDE8B Antibody.| Product Name | PDE8B Antibody |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PDE8B, ADSD, HsPDE8B, PPNAD3, Phosphodiesterase 8B |
| Product description | Phosphodiesterase 8B, is a high affinity, cAMP-specific phosphodiesterase. Enhanced PDE8B activity has been associated with the phenotypic expression of Gsalpha mutations in human pituitary tumors. PDE8B is absent in normal pituitary but present in GH-secreting adenomas. PDE8B activity is inhibited by dipyridamole, but it is insensitive to rolipram, zaprinast, or IBMX. |
| Immunogen | PDE8B antibody was raised against a peptide located near the internal domain of PDE8B (Human). |
| Clonality | Polyclonal |
|---|---|
| Host Species | Rabbit |
| Tested Applications | IHC |
| PDE8B antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
|
| Species Reactivity | GibbonGorillaHumanMonkey |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PDE8B |
|---|---|
| Alternative Names | PDE8B ADSD HsPDE8B PPNAD3 Phosphodiesterase 8B |
| Tissue Specificity | BLAST analysis of the peptide immunogen showed no homology with other human proteins. |
Application
Immunohistochemistry staining of PDE8B in thyroid tissue using PDE8B Antibody.| Application Notes | PDE8B antibody can be used in ELISA, Western Blot starting at 1:500 - 1:1000, immunohistochemistry starting at 5 μg/mL, and immunofluorescence starting at 10 μg/mL.: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | PDE8B antibody should be stored long term (months) at -80 ˚C and short term (days) at 4 ˚C. As with all antibodies avoid freeze/thaw cycles. |
| Storage Buffer | PBS, 0.1% sodium azide. |
