Western blot
Titration: 1.0 ug/mlPositive Control: HepG2 Whole Cell| Product Name | Rabbit anti-PDE8B polyclonal antibody - middle region |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | ADSD, FLJ11212, PPNAD3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Gene Symbol | PDE8B |
|---|---|
| Gene Synonyms | ADSD FLJ11212 PPNAD3 |
| Gene Full Name | Phosphodiesterase 8B |
| Gene Summary | The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene. |
| Alternative Names | ADSD FLJ11212 PPNAD3 |
| Molecular Weight(MW) | 87kDa |
| Sequence | 788 amino acids |
| Entrez Gene | 8622 |
|---|---|
| SwissProt ID | O95263-2 |
| Protein Accession | NP_001025022 |
Western blot
Titration: 1.0 ug/mlPositive Control: HepG2 Whole Cell| Application Notes | WB:1:500~1:2000 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | Aliquot and store at -20°C. Avoid repeated freeze / thaw cycles |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
